| Medusa skull (TibiaPic) | Thais | -3 | 1 |
| Medusa Tower entrance | Port Hope | Surface | 1 |
| Megasylvan Yselda | Newhaven | -5 | 1 |
| Memory box (TibiaEvents) | Thais | -3 | 1 |
| Memory enlightener (use shards here) | Issavi | -2 | 1 |
| Memory task | Blue Valley | Surface | 1 |
| Mephiles (exact spawn tile) | The Void | 3 | 1 |
| Message in a bottle | Roshamuul | Surface | 11 |
| Metal eye (click to put out the fire) | Newhaven | -7 | 1 |
| Metal file | Venore | -6 | 1 |
| Michael the Stalwart (exact spawn tile) | Oramond | 7 | 1 |
| Midnight panther doll (TibiaMagazine) | Thais | -3 | 1 |
| Mimar Haffar | Thalassara | 1, Surface | 3 |
| Mimar Haffar boss room | Moonfall | -8 | 1 |
| Mindmasher (spawn location) | Gray Beach | -1 | 1 |
| Mini NabBot (NabBot) | Thais | -3 | 1 |
| Miraculously burning trees (Blood Brothers quest) | The Void | Surface | 1 |
| Mirror | Issavi | -2 | 2 |
| Mitmah north key | Issavi | -4 | 1 |
| Mitmah south key | Issavi | -3 | 1 |
| Mitmah Vanguard | Issavi | -4 | 1 |
| Mitmah west key | Issavi | -3 | 1 |
| Mole spawn | Darashia | -8 | 7 |
| Monster Graveyard (equip earth + death + fire protection) | Marapur | -8 | 1 |
| Monstor (exact spawn tile) | The Void | 5 | 1 |
| Moohtant Wallbreaker (spawn location) | Rathleton | -6 | 1 |
| Moon mint | Moonfall | Surface | 2 |
| Moon sculpture (use lit moon mirror at night) | Feyrist | 1 | 1 |
| Moonshine pearl | Marapur | Surface | 1 |
| Moonshine Pearl | Moonfall | -1 | 1 |
| Moonspawn Juggernaut (exact spawn tile?) | Salgadara | Surface | 1 |
| Morguthis (exact spawn tile) | Southern Darama | -7 | 1 |
| Mornenion (spawn location) | Venore | Surface | 1 |
| Mosaic | Tiquanda | -1 | 6 |
| Mountain Hideout | Liberty Bay | Surface | 1 |
| Mountain Tomb (boss: Dipthrah) <hidden> | Darashia | Surface | 1 |
| Mouthpiece supply | Darashia | Surface | 1 |
| Mozradek | Issavi | -1 | 1 |
| Mr. Punish (approximate spawn location) | Venore | -8 | 1 |
| MUD | Nostalgia | -8 | 1 |
| Muglex Clan Chief (exact spawn tile) | Newhaven | Surface | 1 |
| Music box (TibiaSpace) | Thais | -3 | 1 |
| Mutagens task | Moonfall | -2 | 1 |
| Mutated glooth (pink) | Rathleton | -5 | 8 |
| Mystic flame | Svargrond | -5, -6 | 3 |
| Mystic flame to NPC A Dragon Mother | Svargrond | -5 | 1 |
| Myzareth's soul cage (use energy damage) | The Void | -8 | 1 |
| Neferi the Spy | Issavi | 1 | 1 |
| Nest (small sapphire) | Darashia | -2 | 1 |
| Nightmare Knights | Venore | -7 | 1 |